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Not necessarily. That depends on personal preference. And IMHO you should enable some language specific filter if you visit sites in other languages than English. And the third party tracking and annoyance filters. Other than that I think the default settings are pretty good as is. But I just see no reason why someone should configure their Android uBlock differnetly than on the desktop… Just use the same settings?!
Hmm. I had another look on my laptop. I might have to revise my answer: I have all the 5 uBlock lists, EasyList plus EasyList Germany and EasyPrivacy… And a few smaller ones are enabled, too. BUT I don’t think those unmaintained lists I mentioned show up in uBlock anyways. So you might be fine enabling all of them.
I still think it doesn’t helps after some point… But it’s definitely not as bad as I said earlier… At some point I’ll have to brush up my knowledge.